| |
Answer:
Fats are the principal source of energy in many organisms as well as
carbohydrates, and other nutrients. Although, the molecular structures
are significantly different, the catabolism is surprisingly similar.
In other words, a variety of molecules with different structures
eventually break down to carbon
dioxide (CO2), water (H2O),
and ATP, which is the currency of energy.
Catabolism follows three common steps for all the nutrients including
fats and carbohydrates. The first step is the conversion of small
molecules of fats and carbohydrates into acetyl-CoA. Next, oxidation
of acetyl-CoA in the citric acid cycle (tricarboxylic
acid cycle ,TCA cycle) yields water,
carbon dioxide, and electrons, simultaneously,
acetyl-CoA changes its form to
various intermediates such as citrate and
fumarate. Carbon dioxide
formed in the second step is released to the outside by the
respiration system and electrons are utilized in the final step, the
electron-transport system. In this step, a number of ATPs
and water are produced by chain reactions. The chemical reaction of the formation
of water can be simply written as 2H+ + 1/2 O2 +
2 e-
→
H2O. In conclusion, no matter what the starting products
are, the basic steps described above are always the same.
Fats and carbohydrates, like two trains converging into one station,
turn to a common compound, acetyl-CoA. However, the difference between
fats and carbohydrates is the process of formation of
acetyl-CoA.
Carbohydrate first decomposes to glucose or other monosaccharides, and
then changes to pyruvate, and finally to acetyl-CoA. On the other
hand, lipid turns to fatty acids and glycerol by digestion, after
that, acetyl-CoA is formed from fatty acids through a process known as
b-oxidation.
Carbohydrates
→
glucose
→
pyruvate
→
acetyl-CoA
Lipids
→
fatty acids + glycerol
→
acetyl-CoA
Excess energy in organisms is usually stored in fat cells in the form
of triacylglycerol. When energy is needed, for example, when exercise
is performed, hormones will trigger activities of triacylglycerol
lipase, which is an important enzyme for fat decomposition. Fats will
be broken down to fatty acids and glycerol by the enzyme, and then
carried by serum albumins in the blood stream to the cells where the
fuel is needed. At the destination, fatty acids enter mitochondria and
the three basic steps (b-oxidation
to acetyl-CoA, TCA cycle, and electron-transfer) will be followed in
order to yield ATP.
It is generally said that twenty-minutes of exercise is necessary to
burn fats efficiently. This is not a myth but a scientifically
understood scenario. The key concept is that enzymes need proper
temperature to work efficiently. In this case, triacylglycerol works
best at the temperature that can be achieved by twenty-minutes of
exercise. Before that, only fatty acids floating in the blood stream
will be used, therefore, at least twenty minutes of exercise are
needed to burn fats in the body.
This article is translated by Chemistryquestion.com from the original article in Chemistryquestion.jp. Please let us know if you find any errors.
(C.H)
|
|